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Neither propoxyphene alone nor in combination with acetaminophen continues to be studied in pediatric patients.
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Overdose of acetaminophen might bring about dose-dependent potentially deadly hepatic toxicity. Early symptoms within just 24 hrs once the overdose may possibly incorporate anorexia, nausea, vomiting, diaphoresis, basic malaise, and abdominal soreness. The affected individual could read more then present no signs or symptoms, but proof of liver dysfunction could come get more info to be obvious up to 72 hours following ingestion, with elevated serum transaminase and lactic dehydrogenase stages, an increase in serum bilirubin concentrations, and a protracted prothrombin time. Death from hepatic failure may perhaps consequence three to 7 times immediately after overdosage.
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